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1fl oz | 30 ml

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Developed with Second Generation Growth Factor Technology, the Cellular Repair Face Serum addresses the multi-level effects of aging, including fine lines wrinkles, elasticity and texture.

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Klotho Skin ingredients are clean, sustainably sourced, and proven effective. All ingredients in Klotho Skin products are sustainably sourced. Klotho Skin products are responsibly packaged, using minimal plastics. Klotho Skin products are cruelty free, with absolutely no animal testing practices.

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Daily use promotes cellular expression of Klotho gene:

  • Increased collagen production, smoothing out fine lines

  • Decreased collagen breakdown, slowing the development of fine lines and wrinkles

  • Decreased TEWL (Transepidermal Water Loss), increasing skin elasticity

  • Increase oxidative stress protection, encouraging even tone and texture

  • Increased anti-inflammatory responses, promoting healthy tone and appearance

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After cleansing and drying face, twist the cap of bottle to dispense serum onto clean hands. Gently pat serum into the skin in a circular motion. Wait 5 minutes for serum to dry and absorb before applying any moisturizer or sunblock.

Best results are seen when applied morning and night. All skin care products should be used for 21 to 28 days prior to evaluation to ensure full cell cycle results.

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Klotho Skin is formulated for all skin types and all ages from clean, sustainably sourced, and proven ingredients: EGF (oligopeptide-1), Vitamin E, Glycerine, Natural Alpha-Hydroxy Acid (AHA) Sodium Hyaluronate, Tetrahexyldecyl Ascorbate, Sorbitol, 1,2-Hexanediol, Cellulose Gum, Caprylyl Glycol, Fruit Oil Extract, Lactic Acid

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Klotho Skin 28-Day Before & After gallery for proven results.


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Pre-orders begin January 2020 & begin shipping May 2020


ONE-TIME purchase


Try Klotho Skin’s Cellular Repair Face Serum once. Once you love the results, have it delivered monthly to your door.



$125 monthly

Enjoy 10% off your monthly subscription purchase to have Klotho Skin delivered to your door.



$210 monthly

Enjoy 15% off your monthly purchase of Klotho Skin’s Cellular Repair Face Serum and Eye Serum system.


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+ What is the difference between serum and cream/moisturizer?

Serums are highly concentrated anti-aging ingredients. Unlike moisturizers, they do not contain occlusive, or airtight, ingredients such as petrolatum or mineral oil that create a barrier on your skin. Because serums do not contain filler ingredients, they penetrate the skin faster and more effectively, requiring minimal amounts of product per application.

Klotho Skin developed a liposome delivery system for its products to allow growth factor proteins that normally could not penetrate the epidermis to reach their target areas. The proprietary technology encodes the product and mimics a transporting fat molecule to allow GF entry and breakdown.

+ What causes fine lines and wrinkles?

Dependent upon your age and skin type, fine lines typically appear around the eyes as signs of dehydration. Over time, the lines become permanent as signs of habitual movements, and moisture and collagen loss through oxidative stress.

As Klotho Skin products promote the upregulation of the Klotho gene, which ultimately increases the body's natural sodium dioxide levels and results in cellular protection against oxidative stress.

+ What is TEWL (Transepidermal Water Loss)?

TEWL is the process in which water passes from the dermis (middle layer) to the epidermis (outer layer) and evaporates from the skin’s surface.

While TEWL is a process that your skin naturally regulates, certain circumstances such as injury, low-humidity weather conditions and topically applied products can damage the skin’s barrier function can dry out the skin and affect TEWL levels.

+ At what age should I begin applying facial serum?

Klotho Skin recommends starting a facial serum at age 20, to encourage hydration and diminish fine lines under the eyes.

+ Is it too late to use facial serum?

It is never too late to take care of your skin. The active ingredients in Klotho Skin products work on all skins, at all ages.

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+ What are Human Fibroblast cells?

Fibroblasts are the main connective tissues found in the body. A fibroblast cell is responsible for building the extracellular matrix (a framework that supports additional structures) and collagen (the element that fills the framework). Together, the matrix and collagen form the structural framework of tissues and play an important role in tissue repair. As the fibroblast ages , collagen production drops almost in half.

Klotho uses fibroblast cells to build collagen-based structures that are then introduced to a promoter gene to get the highest levels of Epidermal Growth Factor (EGF). The factors are then isolated and harvested to set the framework for Klotho activation and its resultant benefits. Studies have shown that fibroblasts treated with Klotho Skin cosmeceuticals can actually start producing collagen like a younger fibroblast cell.

+ What are Second Generation Growth Factors?

Growth Factors are messenger proteins natural to the human body. Their function is to stimulate the renewal and specialization of cells. Each cellular activator has its own unique function and many of them play an important role in the biology of the skin.

Klotho Skin creates Second Generation Growth Factors by isolating human fibroblasts cells and adding a promoter gene to get powerful growth factors, in quality and quanity. Those factors are then collected and added to Klotho serums to maximize skin rejuvenation.

+ Are Klotho Skin products fragrance free?

Klotho Skin uses plant essential oils within its ingredient list. Hints of fruit oil extracts can be recognized.

+ Were animals tested in the making of this product?

No animals were used for testing in the making of Klotho Skin products.

+ Were animals tested in the making of this product?

No animals were used for testing in the making of Klotho Skin products.